A Fully Parameterized Fem Model for Electromagnetic Optimization of an RF Mems Wafer Level Package

In this work, we present a fully parameterized capped transmission line model for electromagnetic optimization of a wafer level package (WLP) for RF MEMS applications using the Ansoft HFSS-TM electromagnetic simulator. All the degrees of freedom (DoF's) in the package fabrication can be modified within the model in order to optimize for losses and mismatch (capacitive and inductive couplings) introduced by the cap affecting the MEMS RF behaviour. Ansoft HFSS-TM was also validated for the simulation of capped RF MEMS devices by comparison against experimental data. A test run of capped 50 transmission lines and shorts was fabricated and tested.Comment: Submitted on behalf of EDA Publishing Association (http://irevues.inist.fr/EDA-Publishing

Parasitic Effects Reduction for Wafer-Level Packaging of RF-Mems

In RF-MEMS packaging, next to the protection of movable structures, optimization of package electrical performance plays a very important role. In this work, a wafer-level packaging process has been investigated and optimized in order to minimize electrical parasitic effects. The RF-MEMS package concept used is based on a wafer-level bonding of a capping silicon substrate to an RF-MEMS wafer. The capping silicon substrate resistivity, substrate thickness and the geometry of through-substrate electrical interconnect vias have been optimized using finite-element electromagnetic simulations (Ansoft HFSS). Test structures for electrical characterization have been designed and after their fabrication, measurement results will be compared with simulations.Comment: Submitted on behalf of TIMA Editions (http://irevues.inist.fr/tima-editions

Measuring the Magnetic Flux Density with Flux Loops and Hall Probes in the CMS Magnet Flux Return Yoke

The Compact Muon Solenoid (CMS) is a general purpose detector, designed to run at the highest luminosity at the CERN Large Hadron Collider (LHC). Its distinctive features include a 4 T superconducting solenoid with 6-m-diameter by 12.5-m-length free bore, enclosed inside a 10,000-ton return yoke made of construction steel. The flux return yoke consists of five dodecagonal three-layered barrel wheels and four end-cap disks at each end comprised of steel blocks up to 620 mm thick, which serve as the absorber plates of the muon detection system. To measure the field in and around the steel, a system of 22 flux loops and 82 3-D Hall sensors is installed on the return yoke blocks. A TOSCA 3-D model of the CMS magnet is developed to describe the magnetic field everywhere outside the tracking volume that was measured with the field-mapping machine. The voltages induced in the flux loops by the magnetic flux changing during the CMS magnet standard ramps down are measured with six 16-bit DAQ modules. The off-line integration of the induced voltages reconstructs the magnetic flux density in the yoke steel blocks at the operational magnet current of 18.164 kA. The results of the flux loop measurements during three magnet ramps down are presented and discussed.Comment: 3 pages, 6 figures, presented at the IEEE Nuclear Science Symposium 2016 (NSS) in Strasbourg, France on November 3, 2016. arXiv admin note: text overlap with arXiv:1605.0877

Flux Loop Measurements of the Magnetic Flux Density in the CMS Magnet Yoke

The Compact Muon Solenoid (CMS) is a general purpose detector, designed to run at the highest luminosity at the CERN Large Hadron Collider (LHC). Its distinctive features include a 4 T superconducting solenoid with 6-m-diameter by 12.5-m-length free bore, enclosed inside a 10,000-ton return yoke made of construction steel. The return yoke consists of five dodecagonal three-layered barrel wheels and four end-cap disks at each end comprised of steel blocks up to 620 mm thick, which serve as the absorber plates of the muon detection system. To measure the field in and around the steel, a system of 22 flux loops and 82 3-D Hall sensors is installed on the return yoke blocks. A TOSCA 3-D model of the CMS magnet is developed to describe the magnetic field everywhere outside the tracking volume measured with the field-mapping machine. The first attempt is made to measure the magnetic flux density in the steel blocks of the CMS magnet yoke using the standard magnet discharge with the current ramp down speed of 1.5 A/s.Comment: 7 pages, 5 figures, presented at ISCM2016 - 5th International Conference on Superconductivity and Magnetism on April 28, 2016 at Fethiye, Turke

Measuring the Magnetic Flux Density in the CMS Steel Yoke

The Compact Muon Solenoid (CMS) is a general purpose detector, designed to run at the highest luminosity at the CERN Large Hadron Collider (LHC). Its distinctive features include a 4 T superconducting solenoid with 6-m-diameter by 12.5-m-length free bore, enclosed inside a 10000-ton return yoke made of construction steel. The return yoke consists of five dodecagonal three-layered barrel wheels and four end-cap disks at each end comprised of steel blocks up to 620 mm thick, which serve as the absorber plates of the muon detection system. Accurate characterization of the magnetic field everywhere in the CMS detector is required. To measure the field in and around the steel, a system of 22 flux-loops and 82 3-D Hall sensors is installed on the return yoke blocks. Fast discharges of the solenoid (190 s time-constant) made during the CMS magnet surface commissioning test at the solenoid central fields of 2.64, 3.16, 3.68 and 4.01 T were used to induce voltages in the flux-loops. The voltages are measured on-line and integrated off-line to obtain the magnetic flux in the steel yoke close to the muon chambers at full excitations of the solenoid. The 3-D Hall sensors installed on the steel-air interfaces give supplementary information on the components of magnetic field and permit to estimate the remanent field in steel to be added to the magnetic flux density obtained by the voltages integration. A TOSCA 3-D model of the CMS magnet is developed to describe the magnetic field everywhere outside the tracking volume measured with the field-mapping machine. The results of the measurements and calculations are presented, compared and discussed.Comment: 9 pages, 7 figures, 16 references, presented at the III International Conference on Superconductivity and Magnetism (ICSM-2012), Kumburgaz, Istanbul, Turkey, 29 April - 4 May 201

Application of a new processing method to post-LDL-apheresis data.

Our aim was to elaborate a method to optimise treatment intervals for the individual low-density lipoprotein (LDL)-apheresis treated patients. After each treatment, plasma LDL concentrations show a time-related increase with a decreasing speed until a maximum level.We searched to interpret the post- LDL-apheresis experimental data trend as the physical process that produces the observed curve, so that the fitting presupposed theoretical function is a direct consequence of the physic process, because to establish the better time. Applying the proposed fitting method to a succession of 15 samples obtained from the mean of six plasmapheresis executed on five different subjects, small estimate standard error (5 mg/dl) and relative error (1.7%) with a dispersion evidently related to the experimental error were observed. Obviously, applying the same method to a single case, the dispersion is more marked (relative error ,5%), with a SE of 10–13 mg/dl, even though the aspect of a casual phenomenon is conserved. Our physical interpretation appears to be a practical model to predict the LDL-rebound kinetic of the single patient

Validation of the CMS Magnetic Field Map

The Compact Muon Solenoid (CMS) is a general purpose detector, designed to run at the highest luminosity at the CERN Large Hadron Collider (LHC). Its distinctive features include a 4 T superconducting solenoid with 6-m-diameter by 12.5-m-length free bore, enclosed inside a 10,000-ton return yoke made of construction steel. The return yoke consists of five dodecagonal three-layered barrel wheels and four end-cap disks at each end comprised of steel blocks up to 620 mm thick, which serve as the absorber plates of the muon detection system. To measure the field in and around the steel, a system of 22 flux loops and 82 3-D Hall sensors is installed on the return yoke blocks. A TOSCA 3-D model of the CMS magnet is developed to describe the magnetic field everywhere outside the tracking volume measured with the field-mapping machine. The magnetic field description is compared with the measurements and discussed.Comment: 7 pages, 5 figures, presented at 4th International Conference on Superconductivity and Magnetism 2014, April 27 - May 2, 2014, Antalya, Turkey. arXiv admin note: substantial text overlap with arXiv:1605.08778; text overlap with arXiv:1212.165

Developing the Technique of Measurements of Magnetic Field in the CMS Steel Yoke Elements With Flux-Loops and Hall Probes

Compact muon solenoid (CMS) is a general-purpose detector designed to run at the highest luminosity at the CERN large hadron collider (LHC). Its distinctive features include a 4 T superconducting solenoid with 6 m diameter by 12.5 m long free bore, enclosed inside a 10000-ton return yoke made of construction steel. Accurate characterization of the magnetic field everywhere in theCMSdetector, including the large ferromagnetic parts of the yoke, is required. To measure the field in and around ferromagnetic parts, a set of flux-loops and Hall probe sensors will be installed on several of the steel pieces. Fast discharges of the solenoid during system commissioning tests will be used to induce voltages in the flux-loops that can be integrated to measure the flux in the steel at full excitation of the solenoid. The Hall sensors will give supplementary information on the axial magnetic field and permit estimation of the remanent field in the steel after the fast discharge. An experimental R&D program has been undertaken, using a test flux-loop, two Hall sensors, and sample disks made from the same construction steel used for the CMS magnet yoke. A sample disc, assembled with the test flux-loop and the Hall sensors, was inserted between the pole tips of a dipole electromagnet equipped with a computer-controlled power supply to measure the excitation of the steel from full saturation to zero field. The results of the measurements are presented and discussed.Comment: 6 pages, 8 figures, 6 reference

Novel Mutation in the Apob Gene (Apo B-15.56): A Case Report

Novel Mutation in the Apob Gene (Apo B-15.56): A Case ReportFamilial hypobetalipoproteinemia (FHBL) is a rare co-dominant genetic disorder characterized by decrease of plasma low density lipoprotein-cholesterol (LDL-c) or apolipoprotein B (Apo-B) equal to or less than the 5th percentile for the population. We describe a 48-year-old male who presented with fatty liver disease (FLD), insulin resistance (IR), obesity and hypertension. Our patient thus met the latest diagnostic criteria of the metabolic syndrome (MS) proposed by the Adult Treatment Panel and the International Diabetes Federation. However, he had very low plasma concentration of LDL-c and Apo-B. DNA sequencing showed that he and two first-degree relatives affected by obesity and mild IR were heterozygous for a single nucleotide deletion on exon 15 of the APOB gene, which was predicted to form a truncated Apo-B designated Apo B-15.56

Practical guidelines for familial combined hyperlipidemia diagnosis: an up-date

Familial combined hyperlidemia (FCH) is a common metabolic disorder characterized by: (a) increase in cholesterolemia and/or triglyceridemia in at least two members of the same family, (b) intra-individual and intrafamilial variability of the lipid phenotype, and (c) increased risk of premature coronary heart disease (CHD). FCH is very frequent and is one of the most common genetic hyperlipidemias in the general population (prevalence estimated: 0.5%–2.0%), being the most frequent in patients affected by CHD (10%) and among acute myocardial infarction survivors aged less than 60 (11.3%). This percentage increases to 40% when all the myocardial infarction survivors are considered without age limits. However, because of the peculiar variability of laboratory parameters, and because of the frequent overlapping with the features of metabolic syndrome, this serious disease is often not recognized and treated. The aim of this review is to define the main characteristics of the disease in order to simplify its detection and early treatment by all physicians by mean of practical guidelines